Melasma mainly influences women; typically appears as tan, brown, or grayish-brown patches on the skin, often on the face, triggered by hormonal changes (such as increased estrogen levels), inflammation or prolonged sun exposure. Up to this date, there is no treatment that can fully cure melasma once it has developed on the face. The science behind melasma is that melanin is shown as patchy discolouration spots at the surface of the face. These melanin are produced by melanocytes (melanin production factories). These melanocytes (melanin production factories) control the melanin at the face automatically, once these melanocytes lose control and start overproducing, they keep producing melanin continuously. There is no treatment to regulate the melanocytes. In YHVH Medical & Aesthetic Clinic, we manage melasma by removing the melanin from the skin surface and quarantine these melanocytes (melanin production factories). We have the following aesthetic treatments to manage melasma.